Shaping clonal hematopoiesis

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Chipping in on clonal hematopoiesis

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Clonal hematopoiesis (CH) in aplastic anemia (AA) has been closely linked to the evolution of late clonal disorders, including paroxysmal nocturnal hemoglobinuria and myelodysplastic syndromes (MDS)/acute myeloid leukemia (AML), which are common complications after successful immunosuppressive therapy (IST). With the advent of high-throughput sequencing of recent years, the molecular aspect of ...

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ژورنال

عنوان ژورنال: Blood

سال: 2020

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.2020005714